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Decreasing Endocrine Disruptor Exposure in Latina Teens Kim Harley of UC Berkeley and Kimberly Parra of Clinica de Salud del Valle Salinas teamed up to determine whether teens can reduce their body burden of potential breast cancer carcinogens by switching to safer cosmetics. They found a significant drop in chemicals levels when teens switched for as few as three day. Intranasal Drug Delivery for Brain Metastatic Breast Cancer Axel Schonthal at the University of Southern California is developing a treatment for breast cancer that metastasizes to the brain. With tax checkoff funding, he produced a compound called TMZ-POH which when delivered through the nose is able to cross the blood-brain barrier and target triple negative breast cancer cells in mice. Intervening on Reproductive Health in Young Survivors Irene Su at UC San Diego is conducting research that will inform and address the unmet reproductive health needs of young breast cancer survivors. She is determining whether the Reproductive Health Survivorship Care Plan will improve estrogen deprivation symptoms, fertility concerns, contraceptive practices and sexual function for these women. Light at Night and Breast Cancer Risk in California Teachers Peggy Reynolds at the Cancer Prevention Institute of California and her colleagues analyzed satellite imagery data and survey data to determine whether outdoor levels of light at night correlates to breast cancer rates. Their findings suggested that women living in the areas with very high levels of outdoor LAN had about a 10% increased risk of breast cancer compared to women who lived in areas with the lowest levels of indoor LAN. Measuring Real-world Breast Cancer Outcomes Allison Kurian at Stanford University investigated how care preference and decision making around emerging treatments compares in academic and community health care settings. She developed the Oncoshare research tool that linked records between the institutions and found that patients treated in two health care systems received much more intensive treatment than others, despite having comparable prognostic factors. Modulation of Breast Cancer Stem Cell response to Radiation Frank Pajonk at UCLA found a way to distinguish breast cancer stem cells, which are responsible for tumor resistance to ionizing radiation, from normal breast cancer stem cells and ultimately led to the discovery that ionizing radiation may increase tumor aggressiveness by causing non-breast cancer stem cells to convert to the cancer stem cells. |
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The California Breast Cancer Research Program (CBCRP) is fighting to end the disease through innovative science and community participation. And with a tax check-off contribution, you can join
the fight.
New approaches, new ideas.
The country's largest state-funded breast cancer research effort, CBCRP is run independently from the state by the University of California.
95% of all donations support new approaches to diagnose, treat and prevent breast cancer. Approaches other agencies might be reluctant to support. Such as:
• Identifying environmental factors that may cause breast cancer.
• Exploring new, effective treatments for advanced and metastatic breast cancer.
• Improving support networks to empower breast cancer patients.
Over $13 million in grants so far. And the fight's not over.
Check the box. Fund the fight. Mark 405 on your 540 Tax Form. It's an easy,
tax-deductible way to help conquer breast cancer.